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. 2023 Mar 22;24(6):5998. doi: 10.3390/ijms24065998

Table 2.

Studies focusing on the electrophysiology of the retina.

Year Title Authors Subjects Element of Study Primary Endpoint Type of Study Outcome
2011 Impact of blue vs. red light on retinal response of patients with seasonal affective disorder and healthy controls Gagné et al. [46] 20 Cones and rods ERG Prospective controlled study Positive: blue light decreases maximal ERG response
2018 Effect of Heat-Killed Lactobacillus paracasei KW3110 Ingestion on Ocular Disorders Caused by Visual Display Terminal (VDT) Loads: A Randomized, Double-Blind, Placebo-Controlled Parallel-Group Study Morita et al. [47] 62 Cones and rods CFF,
VAS,
CS
Prospective, randomized, controlled study Neutral: significant improvement 4 weeks after intake, but not during the 8th week
2021 Blue Light from Cell Phones Can Cause Chronic Retinal Light Injury: The Evidence from a Clinical Observational Study and a SD Rat Model Li et al. [48] 25 Cones and rods mfERG Prospective, randomized, controlled study Positive: reduced amplitude of parafoveal regions

ERG = electroretinogram; CFF = critical flicker frequency; VAS = visual analog scale; mfERG = multifocal ERG.