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Molecular structures: (A) The superimposed structures of the 67B complex with BRD9 and TAF1(2), and 67B in complex with BRD9 (PDB code 5I7X) and 67B bound to TAF1(2) (PDB code 5I29), in which BRD9 is displayed in green and TAF1(2) in magenta with cartoon modes, (B) Binding pockets of BRD9 and TAF1(2) are shown in the surface modes and inhibitor in the stick mode, (C–E) correspond to the structures of 67B, 67C, and 69G, respectively, from which inhibitors are depicted in line forms.
