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. 2023 Mar 28;6(6):e202301914. doi: 10.26508/lsa.202301914

Figure 7. MFN2 oligomerization is influenced by SLC25A46 and OPA1.

Figure 7.

(A) Analysis of MFN2 and OPA1 oligomerization (by BN-PAGE and SDS–PAGE) of isolated mitochondria from control and SLC25A46 knock-out fibroblasts in which MFN2 or OPA1 was knocked down by siRNA constructs for 6 d. siRNA-mediated knock-down of SLC25A46 in control cells is also shown. (B) Immunofluorescence analysis of fibroblasts after 6 d of siRNA-mediated knock-down of MFN2 and OPA1 in control and SLC25A46 knock-out fibroblasts. Mitochondria were decorated with anti-PRDX3 in white and DAPI in blue. Scale bar: 10 μm.