. 2023 Feb 26;15(3):771. doi: 10.3390/pharmaceutics15030771

Table 1.

Diameter by DLS and TEM, PDI, and ζ-potential of Fe₃O₄ and CaCO₃ nanoparticles and different Fe₃O₄@CaCO₃ nanocomposites using a variable amount of magnetic core from 0.45 to 4.5 mg/mL for synthesis.

Initial Amount Fe₃O₄, µg/mL	Hydrodynamic Diameter by DLS, nm	Diameter by TEM, nm		PDI	ζ-Potential, mV	TEM Image (Figure 2)
Initial Amount Fe₃O₄, µg/mL	Hydrodynamic Diameter by DLS, nm	NP	Agglomerate	PDI	ζ-Potential, mV	TEM Image (Figure 2)
4.5	130 ± 2	13 ± 2	107 ± 41	0.211 ± 0.006	−15.0 ± 0.3	C
1.8	118 ± 3	16 ± 2	68 ± 20	0.26 ± 0.01	−14.9 ± 0.3	D
0.9	130 ± 9	18 ± 3	61 ± 19	0.248 ± 0.004	−15.5 ± 0.4	E
0.45	121 ± 6	22 ± 1	—	0.31 ± 0.01	−15.6 ± 0.5	F
Initial Fe₃O₄	88 ± 5	11 ± 4	91 ± 23	0.221 ± 0.004	21.6 ± 0.7	A
Control CaCO₃	204 ± 8	26 ± 3	—	0.14 ± 0.02	−17.3 ± 0.4	B