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. 2023 Feb 26;15(3):771. doi: 10.3390/pharmaceutics15030771

Table 2.

Diameter by DLS and TEM, PDI, ζ-potential, and capacity of DOX-loaded nanocomposites Fe3O4@CaCO3/DOX.

Fe3O4@CaCO3 Amount, mg/mL Hydrodynamic
Diameter by DLS, nm
Diameter by TEM, nm PDI ζ-Potential,
mV
Capacity, µg/mg DOX
Loading Efficiency, %
TEM
Image
Figure 6
NP Agglomerate Shell
3.2 133 ± 3 0.234 ± 0.005 −14.7 ± 0.7 25± 1 79.7 ± 0.2
1.6 130 ± 2 0.192 ± 0.008 −13.0 ± 0.2 45 ± 2 74.7 ± 0.1
1.0 128 ± 3 10 ± 2 75 ± 13 4.6 ± 0.3 0.144 ± 0.006 −18.8 ± 0.6 73.2 ± 0.4 73.2 ± 0.4 A
0.40 129 ± 3 0.130 ± 0.002 −14.9 ± 0.4 160 + 2 64.9 ± 0.6
0.20 135 ± 5 11 ± 3 125 ± 31 18 ± 2 0.14 ± 0.01 −15.0 ± 0.3 295 + 2 59.4 ± 0.3 B
0.10 111 ± 3 9 ± 3 149 ± 45 46 ± 9 0.30 ± 0.01 −16.5 ± 0.3 525 ± 3 52.4 ± 0.4 C
0.050 113 ± 5 9 ± 5 201 ± 35 158 ± 46 0.28 ± 0.03 −12.4 ± 0.2 1045 ± 10 45 ± 2 D
0.025 105 ± 3 0.29 ± 0.01 −19.0 ± 0.5 1900 ± 27 34 ± 4
Initial Fe3O4@CaCO3 121 ± 6 0.31 ± 0.01 −15.6 ± 0.5