Table 2.
Fe3O4@CaCO3 Amount, mg/mL | Hydrodynamic Diameter by DLS, nm |
Diameter by TEM, nm | PDI | ζ-Potential, mV |
Capacity, µg/mg | DOX Loading Efficiency, % |
TEM Image Figure 6 |
||
---|---|---|---|---|---|---|---|---|---|
NP | Agglomerate | Shell | |||||||
3.2 | 133 ± 3 | — | 0.234 ± 0.005 | −14.7 ± 0.7 | 25± 1 | 79.7 ± 0.2 | — | ||
1.6 | 130 ± 2 | — | 0.192 ± 0.008 | −13.0 ± 0.2 | 45 ± 2 | 74.7 ± 0.1 | — | ||
1.0 | 128 ± 3 | 10 ± 2 | 75 ± 13 | 4.6 ± 0.3 | 0.144 ± 0.006 | −18.8 ± 0.6 | 73.2 ± 0.4 | 73.2 ± 0.4 | A |
0.40 | 129 ± 3 | — | 0.130 ± 0.002 | −14.9 ± 0.4 | 160 + 2 | 64.9 ± 0.6 | — | ||
0.20 | 135 ± 5 | 11 ± 3 | 125 ± 31 | 18 ± 2 | 0.14 ± 0.01 | −15.0 ± 0.3 | 295 + 2 | 59.4 ± 0.3 | B |
0.10 | 111 ± 3 | 9 ± 3 | 149 ± 45 | 46 ± 9 | 0.30 ± 0.01 | −16.5 ± 0.3 | 525 ± 3 | 52.4 ± 0.4 | C |
0.050 | 113 ± 5 | 9 ± 5 | 201 ± 35 | 158 ± 46 | 0.28 ± 0.03 | −12.4 ± 0.2 | 1045 ± 10 | 45 ± 2 | D |
0.025 | 105 ± 3 | — | 0.29 ± 0.01 | −19.0 ± 0.5 | 1900 ± 27 | 34 ± 4 | — | ||
Initial Fe3O4@CaCO3 | 121 ± 6 | — | 0.31 ± 0.01 | −15.6 ± 0.5 | — | — | — |