Table 3.
DOX release efficiency from Fe3O4@CaCO3/DOX at pH 4.0–7.4 at 25 °C for 24 h.
| Sample Abbreviation with Capacity |
pH 4.0 | pH 5.0 | pH 6.0 | pH 7.4 | ||||
|---|---|---|---|---|---|---|---|---|
| C DOX, % |
C DOX, µg/mL |
C DOX, % |
C DOX, µg/mL |
C DOX, % |
C DOX, µg/mL |
C DOX, % |
C DOX, µg/mL |
|
| Fe3O4@CaCO3/DOX25 | 98 ± 4 | 2.4 ± 0.1 | 99 ± 1 | 2.48 ± 0.03 | 68 ± 3 | 1.69 ± 0.05 | 60 ± 4 | 1.5 ± 0.1 |
| Fe3O4@CaCO3/DOX45 | 94 ± 6 | 4.2 ± 0.3 | 98 ± 2 | 4.41 ± 0.09 | 49 ± 4 | 2.2 ± 0.2 | 57 ± 4 | 2.6 ± 0.1 |
| Fe3O4@CaCO3/DOX73 | 71 ± 5 | 5.2 ± 0.4 | 65 ± 4 | 4.8 ± 0.3 | 38 ± 1 | 2.8 ± 0.1 | 37 ± 4 | 2.7 ± 0.1 |
| Fe3O4@CaCO3/DOX160 | 65 ± 6 | 10 ± 1 | 59 ± 5 | 9.4 ± 0.8 | 26 ± 2 | 4.2 ± 0.3 | 21 ± 2 | 3.4 ± 0.1 |
| Fe3O4@CaCO3DOX295 | 44 ± 4 | 13 ± 1 | 32 ± 3 | 9.4 ± 0.9 | 17 ± 1 | 5.0 ± 0.3 | 12 ± 2 | 3.5 ± 0.1 |
| Fe3O4@CaCO3/DOX525 | 23 ± 2 | 12 ± 1 | 25 ± 2 | 13 ± 1 | 11.4 ± 0.4 | 6.0 ± 0.2 | 9 ± 3 | 4.7 ± 0.2 |
| Fe3O4@CaCO3/DOX1045 | 23 ± 2 | 24 ± 2 | 25 ± 3 | 26 ± 3 | 11.1 ± 0.8 | 12.1 ± 0.8 | 7 ± 2 | 7.3 ± 0.2 |
| Fe3O4@CaCO3/DOX1900 | 21 ± 2 | 44 ± 4 | 17 ± 1 | 32 ± 2 | 6.8 ± 0.5 | 13 ± 1 | 4 ± 1 | 7.6 ± 0.3 |