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IC 50 of different types of Fe3O4@CaCO3/DOX and free DOX on HeLa and MCF-7 cells.
| Sample | HeLa | MCF-7 | ||
|---|---|---|---|---|
| IC 50, µM DOX |
IC 50, µg/mL Fe3O4@CaCO3/DOX | IC 50, µM DOX |
IC 50, µg/mL Fe3O4@CaCO3/DOX | |
| Fe3O4@CaCO3/DOX25 | 3.0 | 49.5 | 5.2 | 60.0 |
| Fe3O4@CaCO3/DOX45 | 1.8 | 22.0 | 4.5 | 41.6 |
| Fe3O4@CaCO3/DOX73 | 1.6 | 13.8 | 2.5 | 16.4 |
| Fe3O4@CaCO3/DOX160 | 1.2 | 7.0 | 2.0 | 9.9 |
| Fe3O4@CaCO3/DOX295 | 2.3 | 5.8 | 2.2 | 7.6 |
| Fe3O4@CaCO3/DOX525 | 2.4 | 2.4 | 3.1 | 4.3 |
| Fe3O4@CaCO3/DOX1045 | 2.5 | 1.9 | 5.2 | 4.1 |
| Fe3O4@CaCO3/DOX1900 | 2.6 | 1.5 | 5.7 | 3.5 |
| DOX | 2.8 | — | 3.1 | — |
