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. 2023 Mar 1;15(3):803. doi: 10.3390/pharmaceutics15030803

Table 5.

IC50 values and inhibition mode of the epigallocatechin molecules.

Virus Protease Molecule IC50 [µM] Inhibition Mode
EGCG 6.3 ± 1.0 Noncompetitive
DENV2 EGC 145 ± 3.0 Competitive
AcEGCG 39.8 ± 2.5 Noncompetitive
EGCG 8 ± 1.4 Noncompetitive
YFV EGC 19 ± 1.9 Competitive
AcEGCG 39.1 ± 2.2 Noncompetitive
EGCG 4.5 ± 0.6 Noncompetitive
ZIKV EGC 8.9 ± 1.2 Competitive
AcEGCG 102 ± 2.6 Noncompetitive
EGCG 1.8 ± 0.5 Noncompetitive
WNV EGC 17.3 ± 2.5 Competitive
AcEGCG 83.4 ± 10.4 Noncompetitive