Table 2.
Examples of right ventricular–pulmonary arterial coupling surrogate parameters and cut‐off values for prediction of events
| Prediction of event | Parameter | Cut‐off value |
|---|---|---|
| Uncoupling measured by gold‐standard Ees/Ea in patients with PAH 29 | TAPSE/PASP | <0.31 mm/mmHg |
| Mortality during follow‐up after significant secondary tricuspid regurgitation diagnosis 50 | TAPSE/PASP | <0.31 mm/mmHg |
| Mortality in patients with heart failure 30 | TAPSE/PASP | <0.36 mm/mmHg |
| Transplant‐free survival in patients with PH 25 | SV/ESV | >0.515 |
| Adverse outcomes in patients with precapillary PH 63 | RVEF/PASP | <0.44%/mmHg |
| Response to CRT 39 , a |
RVGLS/PASP RVFWLS/PASP |
>0.35%/mmHg >0.41%/mmHg |
| 12 month mortality in outpatients with stable heart failure 40 , a |
RVGLS/PASP RVFWLS/PASP |
<0.36%/mmHg <0.65%/mmHg |
| Poor prognosis and RV/LV maladaptation 44 | TAPSE/PASP | <0.38 mm/mmHg |
CRT, cardiac resynchronization therapy; Ea, arterial elastance; Ees, end‐systolic elastance; ESV, end‐systolic volume; LV, left ventricular; PAH, pulmonary arterial hypertension; PASP, pulmonary arterial systolic pressure; PH, pulmonary hypertension; RV, right ventricular; RVEF, right ventricular ejection fraction; RVFWLS, right ventricular free wall longitudinal strain; RVGLS, right ventricular global longitudinal strain; SV, stroke volume; TAPSE, tricuspid annular plane systolic excursion.
a
Authors excluded minus sign for strain.