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Schematic depiction of the SARS-CoV-2 genomic arrangement and proteins (top). Outline of the specific amino acid exchanges compared with the index virus in an early European Feb 2020 SARS-CoV-2 isolate (NL-02-2020), and five variants of concern in the order of appearance: Beta (B.1.351), Alpha (B.1.1.7), Gamma (P.1), Delta (B.1.617.2), and Omicron (BA.1, B.1.1.529) as assessed by next-generation sequencing assembly of the full genome.
