3D EngNT	3D Engineered neural tissue
ATCC	American Type Culture Collection
BDNF	Brain-derived neurotrophic factor
CB1R	cannabinoid receptor 1
CB2R	cannabinoid receptor 2
COX-2	Cyclooxygenase-2
DMEM	Dulbecco’s modified Eagle’s medium
ELISA	Enzyme-Linked Immunosorbent Assay
EMA	European Medicines Agency
ERb	Estrogen Receptor beta
Equisetum A.L.	Equisetum arvense L.
FAAH	Fatty acid amide hydrolase
FBS	foetal bovine serum
FDA	US Food and Drug Administration
GABA	gamma-amino butyric acid
GAD	Glutamic acid decarboxylase
GGF	glial growth factor 2
IASP	International Association for the Study of Pain
IL-1β	Interleukin-1 beta
IL-2	I nterleukin-2
MEM	Minimum Essential Medium
MPZ	Myelin protein zero
MTT	3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
NGF	Nerve growth factor
NP	neuropathic pain
NRG1	Neuregulin 1
OS	oxidative stress
Papp	apparent permeability coefficient
PBS	phosphate buffered saline
PEA	palmitoylethanolamide
PEA-um	ultra-micronized PEA
PEAm	micronized PEA
PNI	peripheral nervous injury
PNS	peripheral nervous system
PVDF	polyvinylidene difluoride
RNS	Radical nitrogen species
ROS	radical oxygen species
RPMI	Roswell Park Memorial Institute-1640
RSC-96	Rat-derived Schwann
SIRT1	sirtuin 1
SIRT3	sirtuin 3
TEER	transepithelial electrical resistance
TJ	Tigh Junction
TNFα	Tumour Necrosis Factor alpha
ZO-1	Human Tight Junction Protein 1