TABLE 5.
Comparation | Azvudine (N = 156) | EAs = 110 | Placebo (N = 156) | EAs = 112 | ||||
Classification | Grade 1 | Grade 2 | Grade 1 | Grade 2 | ||||
Case | Subject (%) | Case | Subject (%) | Case | Subject (%) | Case | Subject (%) | |
Headache | 17 | 10.89 | 0 | 0 | 19 | 12,17 | 0 | 0 |
Dizziness | 16 | 10.25 | 0 | 0 | 19 | 12.17 | 0 | 0 |
AST increase | 11 | 7.05 | 0 | 0 | 10 | 6.41 | 0 | 0 |
Nausea | 10 | 6.4 | 0 | 0 | 9 | 5.76 | 0 | 0 |
Alt increase | 8 | 5.12 | 0 | 0 | 6 | 3.84 | 0 | 0 |
Dimer increase d | 4 | 2.56 | 0 | 0 | 7 | 4.48 | 0 | 0 |
Hyperglycemia | 4 | 2.56 | 0 | 0 | 5 | 3.20 | 0 | 0 |
IB increase | 4 | 2.56 | 0 | 0 | 4 | 2.56 | 0 | 0 |
GGT increase | 5 | 3,20 | 0 | 0 | 3 | 1.92 | 0 | 0 |
PCR-US reduction | 1 | 0 | 0 | 7 | 4.48 | 0 | 0 | |
GGT reduction | 4 | 2.56 | 0 | 0 | 2 | 1.28 | 0 | 0 |
AST reduction | 2 | 1.28 | 0 | 0 | 3 | 1.92 | 0 | 0 |
BD increase | 3 | 1.92 | 0 | 0 | 1 | 0.64 | 0 | 0 |
BD reduction | 1 | 0.64 | 0 | 0 | 2 | 1.28 | 0 | 0 |
ALT reduction | 2 | 1.28 | 0 | 0 | 1 | 0.64 | 0 | 0 |
Potassium increase | 3 | 1.92 | 0 | 0 | 0 | 0 | 0 | 0 |
Palpitation | 0 | 0 | 1 | 0.64 | 0 | 0 | 1 | 0.64 |
CPK-MB increase | 0 | 0 | 0 | 0 | 2 | 1.28 | 0 | 0 |
Chest pain | 0 | 0 | 0 | 0 | 2 | 1.28 | 0 | 0 |
Pregnancy | 0 | 0 | 1 | 0.64 | 0 | 0 | 0 | 0 |
Hypotension | 1 | 0.64 | 0 | 0 | 1 | 0.64 | 0 | 0 |
Leukocytes increase | 2 | 1.28 | 0 | 0 | 0 | 0 | 0 | 0 |
PCR-US increase | 1 | 0.64 | 0 | 0 | 0 | 0 | 0 | 0 |
IB reduction | 0 | 0 | 0 | 0 | 1 | 0.64 | 0 | 0 |
Lymphocyte reduction | 1 | 0,64 | 0 | 0 | 0 | 0 | 0 | 0 |
Arrhythmia | 0 | 0 | 1 | 0.64 | 0 | 0 | 0 | 0 |
Precordial pain | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1.28 |
Abdominal pain | 1 | 0.64 | 0 | 0 | 0 | 0 | 0 | 0 |
Backache | 0 | 0 | 0 | 0 | 1 | 0.64 | 0 | 0 |
Bradicardia | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0.64 |
Arterial hypertension | 0 | 0 | 0 | 0 | 1 | 0.64 | 0 | 0 |
Epigastralgia | 0 | 0 | 0 | 0 | 1 | 0.64 | 0 | 0 |
Anxiety | 1 | 0.64 | 0 | 0 | 0 | 0 | 0 | 0 |
Sodium reduction | 1 | 0.64 | 0 | 0 | 0 | 0 | 0 | 0 |
Potassium reduction | 1 | 0.64 | 0 | 0 | 0 | 0 | 0 | 0 |
Tremor in hands | 1 | 0.64 | 0 | 0 | 0 | 0 | 0 | 0 |
Skin forming | 0 | 0 | 0 | 0 | 1 | 0.64 | 0 | 0 |
CPK-MB Reduction | 1 | 0.64 | 0 | 0 | 0 | 0 | 0 | 0 |
Troponin I reduction | 1 | 0.64 | 0 | 0 | 0 | 0 | 0 | 0 |
Total partial | 107 | 67.87 | 3 | 1.92 | 108 | 69.15 | 4 | 2.56 |