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. 2023 Mar 14;10:1143485. doi: 10.3389/fmed.2023.1143485

TABLE 5.

Consolidated report of adverse events.

Comparation Azvudine (N = 156) EAs = 110 Placebo (N = 156) EAs = 112
Classification Grade 1 Grade 2 Grade 1 Grade 2
Case Subject (%) Case Subject (%) Case Subject (%) Case Subject (%)
Headache 17 10.89 0 0 19 12,17 0 0
Dizziness 16 10.25 0 0 19 12.17 0 0
AST increase 11 7.05 0 0 10 6.41 0 0
Nausea 10 6.4 0 0 9 5.76 0 0
Alt increase 8 5.12 0 0 6 3.84 0 0
Dimer increase d 4 2.56 0 0 7 4.48 0 0
Hyperglycemia 4 2.56 0 0 5 3.20 0 0
IB increase 4 2.56 0 0 4 2.56 0 0
GGT increase 5 3,20 0 0 3 1.92 0 0
PCR-US reduction 1 0 0 7 4.48 0 0
GGT reduction 4 2.56 0 0 2 1.28 0 0
AST reduction 2 1.28 0 0 3 1.92 0 0
BD increase 3 1.92 0 0 1 0.64 0 0
BD reduction 1 0.64 0 0 2 1.28 0 0
ALT reduction 2 1.28 0 0 1 0.64 0 0
Potassium increase 3 1.92 0 0 0 0 0 0
Palpitation 0 0 1 0.64 0 0 1 0.64
CPK-MB increase 0 0 0 0 2 1.28 0 0
Chest pain 0 0 0 0 2 1.28 0 0
Pregnancy 0 0 1 0.64 0 0 0 0
Hypotension 1 0.64 0 0 1 0.64 0 0
Leukocytes increase 2 1.28 0 0 0 0 0 0
PCR-US increase 1 0.64 0 0 0 0 0 0
IB reduction 0 0 0 0 1 0.64 0 0
Lymphocyte reduction 1 0,64 0 0 0 0 0 0
Arrhythmia 0 0 1 0.64 0 0 0 0
Precordial pain 0 0 0 0 0 0 2 1.28
Abdominal pain 1 0.64 0 0 0 0 0 0
Backache 0 0 0 0 1 0.64 0 0
Bradicardia 0 0 0 0 0 0 1 0.64
Arterial hypertension 0 0 0 0 1 0.64 0 0
Epigastralgia 0 0 0 0 1 0.64 0 0
Anxiety 1 0.64 0 0 0 0 0 0
Sodium reduction 1 0.64 0 0 0 0 0 0
Potassium reduction 1 0.64 0 0 0 0 0 0
Tremor in hands 1 0.64 0 0 0 0 0 0
Skin forming 0 0 0 0 1 0.64 0 0
CPK-MB Reduction 1 0.64 0 0 0 0 0 0
Troponin I reduction 1 0.64 0 0 0 0 0 0
Total partial 107 67.87 3 1.92 108 69.15 4 2.56