Table 1.
Baseline characteristics of the patients.
| Eze/Ros 10/20 mg + Tel 80 mg (n = 60) | Eze/Ros 10/20 mg (n = 60) |
Tel 80 mg (n = 60) |
p-Value | |
|---|---|---|---|---|
| Age (years) | 64.82 ± 10.07 | 62.92 ± 8.72 | 65.52 ± 10.63 | 0.1787 |
| Sex, Male, n (%) | 40 (66.67) | 40 (66.67) | 41 (68.33) | 0.9751 |
| Height (cm) | 163.20 ± 8.20 | 163.82 ± 8.54 | 163.22 ± 8.98 | 0.9053 |
| Weight (kg) | 69.39 ± 11.58 | 69.83 ± 12.42 | 69.62 ± 11.72 | 0.9736 |
| BMI (kg/m2) | 25.96 ± 3.18 | 25.91 ± 3.36 | 25.98 ± 2.70 | 0.9526 |
| CHD risk factors, n (%) | ||||
| Smoking | 12 (20.00) | 11 (18.33) | 7 (11.67) | 0.0776 |
| DBP ≥ 90 mmHg | 28 (46.67) | 30 (50.00) | 28 (46.67) | 0.9148 |
| HDL-C < 40 mg/dL | 19 (31.67) | 9 (15.00) | 13 (21.67) | 0.0907 |
| Family history of premature CHD | 4 (6.67) | 1 (1.67) | 1 (1.67) | 0.3702 |
| (−) HDL-C ≥ 60 mg/dL | 12 (20.00) | 16 (26.67) | 12 (20.00) | 0.5979 |
| Diabetes mellitus | 23 (38.33) | 25 (41.67) | 18 (30.00) | 0.3934 |
| Coronary arterial disease | 11 (18.33) | 15 (25.00) | 9 (15.00) | 0.3704 |
| 10-y risk > 20% | 12 (20.00) | 6 (10.00) | 7 (11.67) | 0.2369 |
| Duration of hypertension (months) | 112.03 ± 104.25 | 108.73 ± 71.22 | 101.66 ± 83.45 | 0.6564 |
| Duration of hyperlipidemia (months) | 87.74 ± 78.34 | 83.94 ± 54.20 | 76.35 ± 56.68 | 0.7049 |
| Baseline values | ||||
| MSSBP (mmHg) | 152.41 ± 9.69 | 154.91 ± 10.83 | 152.73 ± 9.15 | 0.3260 |
| MSDBP (mmHg) | 88.59 ± 10.59 | 89.74 ± 9.04 | 87.85 ± 9.84 | 0.5693 |
| Pulse (beats/min) | 70.62 ± 10.02 | 70.77 ± 9.49 | 72.25 ± 12.47 | 0.6124 |
| Total Cholesterol (mg/dL) | 209.45 ± 37.51 | 217.47 ± 32.27 | 217.87 ± 31.65 | 0.2739 |
| Triglyceride (mg/dL) | 162.32 ± 67.02 | 146.17 ± 61.72 | 158.07 ± 69.49 | 0.3763 |
| HDL-C (mg/dL) | 48.27 ± 12.47 | 50.97 ± 12.59 | 49.42 ± 11.57 | 0.4873 |
| LDL-C (mg/dL) | 149.28 ± 30.54 | 156.12 ± 29.99 | 156.55 ± 29.82 | 0.3894 |
| HbA1c (%) | 6.21 ± 0.83 | 6.13 ± 0.70 | 6.06 ± 0.68 | 0.7075 |
| Risk group classification, n (%) | ||||
| Group 1 (risk factor 0–1) | 4 (6.67) | 2 (3.33) | 3 (5.00) | |
| Group 2 (risk factor ≥ 2 and 10-year risk ≤ 20%) | 8 (13.33) | 9 (15.00) | 9 (15.00) | |
| Group 3 (CHD or CHD equivalence or 10-year risk >20%) | 46 (76.67) | 47 (78.33) | 47 (78.33) |
Data are mean values ± SD or n (%). BMI, body mass index; CHD, coronary heart disease; DBP, diastolic blood pressure; Eze, ezetimibe; HDL-C, high-density-lipoprotein cholesterol; LDL-C, low-density-lipoprotein cholesterol; MSDBP, mean sitting diastolic blood pressure; MSSBP, mean sitting systolic blood pressure; Ros, rosuvastatin; Tel, telmisartan.