Skip to main content
. Author manuscript; available in PMC: 2023 Mar 29.
Published in final edited form as: Science. 2022 Jun 10;376(6598):eabm9326. doi: 10.1126/science.abm9326

Fig. 6. Nup155 and other membrane-anchoring domains in the CR.

Fig. 6.

(A) AlphaFold-predicted full-length Nup155. (B) Fitting of the C-terminal region of Nup155 into the cryo-EM density (contour level, 4.5 σ). (C) Interaction of Nup155 with the neighboring inner Nup160 and Nup205 (contour level, 4.5 σ). (D) β-propeller domains of Nup155, Nup133, and Nup160 all localize to the membrane envelope region of the cryo-EM density map of NPC CR full ring at 14.6 Å resolution (contour level, 3.0 σ).