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. 2023 Mar 13;19(1):2182527. doi: 10.1080/21645515.2023.2182527

Table 2.

Summary of lymphocyte transformation test (LTT) results for Patient 1 and Patient 2.

  COVID-19 vaccine
Vaccine components
ChAdOx1
BNT162b2
NVX-CoV2373
Polysorbate 80
PEG 2050
ANOVA SI ANOVA SI ANOVA SI ANOVA SI ANOVA SI
Patient 1 LTT Dilution 1 *** 5.4 NS 1.5     ** 4.0 NS 1.0
Dilution 2 **** 6.3 NS 1.5     **** 5.9 NS 2.7
Dilution 3 **** 6.3 NS 1.6     NS 2.8 NS 2.6
Dilution 4 *** 6.2 NS 1.5     NS 2.2 NS 1.8
Dilution 5 NS 5.3 NS 1.3     NS 1.5 NS 1.7
Dilution 6 NS 3.5 NS 2     NS 1.2 NS 0.3
CD3/CD28 **** 8.7        
PHA **** 7.8    
Patient 2 First LTT Dilution 1 NS 0.5 NS 1.1     NS 0 NS 1.2
Dilution 2 NS 0.6 ** 2.0 NS 0.9 NS 1.2
Dilution 3 NS 0.7 NS 1.1 NS 1.5 NS 1.1
Dilution 4 NS 1.1 NS 1.0 NS 1.5 NS 1.1
Dilution 5 NS 0.9 NS 1.2 NS 1.1 NS 0.8
Dilution 6 NS 0.9 NS 1.0 NS 1.1 NS 1.1
CD3/CD28 NNS 1.16        
PHA NNS 1.32    
Post infection Dilution 1 NS 1.83 NS
(AD)
<2
(AD)
*** 11.1 NS
(AD)
<2
(AD)
NS
(AD)
<2
(AD)
Dilution 2 ** 2.2 **** 19.8
Dilution 3 ** 2.2 **** 12.8
Dilution 4 ** 2.2 ** 9.3
Dilution 5 * 2.1 * 7.68
Dilution 6 ** 2.5 NS 2.8
CD3/CD28 **** 4.1                
PHA **** 3.2                

NS = Not significant, ANOVA *p < .05, **p < .01 and ***p < .001 ****p < .0001.

SI greater > 2 Positive. (AD) = All dilutions.