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. 2023 Mar 9;13(3):409. doi: 10.3390/metabo13030409

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(a) Volcano plot showing DEGs between metabolic subtype-1 and subtype-2 samples. (b) Venn diagram showing the overlap of DEGs between metabolic subtype-1 vs. metabolic subtype-2 and normal vs. tumor comparisons (subtype-2_up: upregulated genes in metabolic subtype-2, subtype-2_down: downregulated genes in metabolic subtype-2, tumor_up: upregulated genes in the tumor, tumor_down: downregulated genes in the tumor). Venny 2.1 was used to generate the Venn diagrams. (c) Metabolic pathways altered in EC and metabolic subtype-2 samples. Orange and pink colors represent upregulated genes in normal vs. tumor conditions and metabolic subtype-1 vs. metabolic subtype-2 conditions, respectively.