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. 2023 Feb 28;15(3):647. doi: 10.3390/v15030647

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Evaluation of cellular uptake of fluorescent N7G, N8G, and N9G samples (CS NPs loaded with foscarnet). HELF cells (human embryonic lung fibroblasts) were incubated with the formulation for the periods indicated and then analyzed by confocal laser scanning microscopy without fixation at 1, 3, and 24 h post-treatment (hpt). The upper panels show fluorescent images while the lower panels show fluorescent images merged with phase-contrast images [256]. Reproduced with permission from Elsevier (Copyright © 2014).