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. 2023 Feb 23;16(3):341. doi: 10.3390/ph16030341

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Structures of thiocarbohydrazones 1–4 investigated in this study, along with structurally similar thiosemicarbazones (triapine) that possess anticancer properties, and TSC24, which additionally inhibits the human DNA topoisomerase IIα.