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(A) Schema of CpG dinucleotides within the human CYP11B1 gene promoter. Open circle denotes CpG dinucleotides (cited from Ref. [88]). (B) Methylation ratios of CYP11B1 were significantly decreased in adenomas of Cushing’s syndrome. * p < 0.05 compared to other tissues; NFA, non-functioning adrenal adenoma; Ad, adjacent adrenal tissue; WBC, white blood cell.
