Skip to main content
. Author manuscript; available in PMC: 2023 Mar 29.
Published in final edited form as: Annu Rev Genet. 2022 Jul 29;56:113–143. doi: 10.1146/annurev-genet-072920-125226

Figure 6. Mitotic drive in D. melanogaster GSCs:

Figure 6.

Mechanisms of the mitotic drive. (A) Stronger centromeres build larger kinetochores that bind more microtubules compared with weaker centromeres. (B) Sister chromatids with asymmetric histone epigenome in male GSCs. A temporal asymmetry of microtubules activity, NEBD, and CENP-A epigenetic asymmetry tightly coordinate to ensure non-random segregation.