Table 8.
Multivariate relative excess risk (RER) of death from vulvar squamous cell carcinoma at five years since diagnosis conditional on having survived two years, by age group at diagnosis, geographic area, and period of diagnosis. Italy, 1990–2015 (total resident female population 15,358,161 in 2015).
| Deaths, n (%) | RER (95% CI) * | p-Value † | |
|---|---|---|---|
| Age group | <0.001 | ||
| 15–69 years | 462 (35.6) | 1.00 (ref) | |
| 70–79 years | 842 (59.0) | 1.33 (1.11–1.60) | |
| ≥80 years | 747 (74.3) | 1.55 (1.20–1.99) | |
| Geographic area | 0.003 | ||
| North | 1362 (55.4) | 1.00 (ref) | |
| Centre | 325 (63.4) | 1.10 (0.86–1.40) | |
| South | 364 (47.8) | 1.43 (1.17–1.74) | |
| Period of diagnosis | 0.073 | ||
| 1990–2002 | 1147 (75.7) | 1.00 (ref) | |
| 2003–2015 | 904 (40.8) | 1.18 (0.98–1.42) |
CI, confidence interval. * Estimates were performed adjusting for all variables in the Table. The RER of death is from a flexible parametric model for net survival with six knots, i.e., the model with the lowest Akaike information criterion. † p-values are for the Wald test.