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. 2023 Mar 16;11(3):678. doi: 10.3390/vaccines11030678

Figure 2.

Figure 2

Immunogenicity of OC COVID-eVax vaccine delivered by EP: (A) Groups of C57Bl/6 mice (n = 5) were vaccinated on Days 0 and 28 and sacrificed on Day 35 for IFN-γ ELISpot analysis. Sera were collected on Days 28 and 35 for binding antibodies titer analysis: (B) IFNγ-producing T cells measured by ELISpot assay on splenocytes restimulated with RBD peptide pool; (C) Total RBD-specific IgG endpoint titers measured by ELISA assay in sera collected on Days 28 and 35. Each symbol represents an individual sample with the error bars representing the SEM. Significance was determined using Mann–Whitney test.