Fig. 2. Identification of mutations that aggravate the intracellular growth defect of Δsde.

(A-C) BMDMs were challenged with WT (Lp02) or noted L. pneumophila mutants expressing luciferase (PahpC::lux). Intracellular growth was determined by measuring luminescence hourly. Data shown and error bars are mean ± SEM at 12 hr increments (mean of 3 technical replicates and a representative of 3 biological replicates).