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[Preprint]. 2023 Mar 24:2023.03.23.533923. [Version 1] doi: 10.1101/2023.03.23.533923

Figure 2. Development of CD4mc Piperidine Analogs.

Figure 2.

Structure of the complex of (+)-BNM-III-170 (PDB code: 6UT1) (A) and (S)-MCG-IV-210 (PDB code: 6USW) (C) bound to clade A/E gp120CRF01 LMHT core [10, 18]. H-bonds are shown as blue dashed lines and other contacts to Gly472 Met 426and Asp368 as grey dashed lines. (B) Graphical illustration of (+)-BNM-III-170 in contact with Gly472 and Met426. (D) Graphical illustration of (S)-MCG-IV-210 in contact with Gly472.