Extended Data Figure 2. Jackknife resampling shows robustness of variation explained by subject covariate in mixed effect model.

A jackknife was performed subsampling 80% of subjects with repeat samples and 80% of subjects without repeat samples to assess robustness of intra-patient stability estimates for cell frequencies (a), gene expression (b), serum protein data (c), gene expression modules (d), serum protein modules (e). 100 replicates of subsampling were performed. Points represent mean variance explained by subject across all replicates and error bars denote 95% confidence intervals (2.5 % and 97.5 % quantiles across jackknife replicates). CBC = complete blood count. TBNK = lymphocyte (T, B, NK cell) phenotyping.