Table A19.
Methods | Type of study: Interventional study Study design: Retrospective case series with prospectively collected data |
Participants | Country: the Netherlands Number of individuals with keratoconus: 19 Number of eyes: 22 Subgroups: preoperative, 1 month postoperative, 6 months postoperative, 18 months postoperative Inclusion criteria: progressive keratoconus stage III-IV, K max > 67.5D, BSCVA < 20/60, keratoconus progression (Δ simK ≥ 1D ± Δ Kmax ≥ 2D) and visual acuity loss, illegibility for cross-linking/ring segments, informed consent Exclusion criteria: - |
Interventions | Donor tissue: artificial anterior chamber, epithelial removal (surgical spears), superficial incision (30G needle), peeling Bowman layer (custom-made stripper, DORC International), ethanol 70%, organ culture medium Surgical technique: mid-stromal pocket, glide (Visitec Surgical Glide), air removal, 70% ethanol, BSS, trypan blue, Bowman layer placement on the glide, graft insertion into stromal pocket, BSS in anterior chamber Postoperative medication: chloramphenicol eye drops 0.5% 6x/day, dexamethasone eye drops 0.1% 4x/day |
Outcomes | BSCVA (logMAR), BCLVA (logMAR), mean anterior simulated keratometry value (D), K max (D), mean posterior keratometry value (D), central corneal thickness (μm), thinnest point thickness (μm), endothelial cell density (cells/mm2), refraction (D), intra-operative and postoperative complications |