Table A22.

Van Dijk 2018 [37].

Methods	Type of study: Interventional study Study design: Prospective case series
Participants	Country: the Netherlands Number of individuals with keratoconus: 17 Number of eyes with keratoconus: 20 Number of untreated contralateral eyes: 16 Subgroups: preoperative, 1 month postoperative, 1 year postoperative, 2 years postoperative, 3 years postoperative, 4 years postoperative, 5 years postoperative Inclusion criteria: BL transplantation between 2010 and 2012 for progressive keratoconus stages III to IV (progression (simK 1D Δ ± Kmax 2D Δ), follow-up ≥ 5 years, ineligibility for UV-crosslinking or ICRS Exclusion criteria: -
Interventions	Donor tissue: artificial anterior chamber, epithelial removal (surgical spears), superficial incision (30G needle), lifting of BL edge (McPherson forceps), peeling Bowman layer (McPherson forceps custom-made stripper, DORC International), ethanol 70%, organ culture medium Surgical technique: mid-stromal pocket, glide (Visitec Surgical Glide), air removal, 70% ethanol, BSS, trypan blue 0.06%, Bowman layer placement on the glide, graft insertion into stromal pocket, BSS in anterior chamber Graft size 9–11 mm Postoperative medication: chloramphenicol eye drops 0.5% 6x/day (1 month), dexamethasone eye drops 0.1% 4x/day (1 month), followed by FML 0.1% 4x/day, tapered to 1x/day over a period of 1 year
Outcomes	BSCVA (LogMAR, Snellen), BCLVA (LogMAR, Snellen), pachymetry thinnest point (μm), pachymetry central point (μm), Kmax (D), Kmean (D), densitometry 0–12 mm (GSU), endothelial cell density (cells/mm2), complications, success rate at 5 years, progression of untreated contralateral eyes