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. 2023 Mar 1;14(13):3493–3500. doi: 10.1039/d2sc06152j

Reaction scope for the formation of chromeno[3,4-c]pyrroles 2a.

graphic file with name d2sc06152j-u2.jpg
a

Reaction conditions: 1 (0.1 mmol), Cu(CH3CN)4PF6 (0.01 mmol), NaBArF4 (0.012 mmol), (±)-BINAP (0.012 mmol), DCE (2 mL), 40 °C, 12 h, in vials; yields are for the isolated products.

b

Formed from ynamide substrate 1ag. Ts = p-toluenesulfonyl. MBS = 4-methoxybenzenesulfonyl.