Reaction scope for the formation of chromeno[3,4-c]pyrroles 2a.
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Reaction conditions: 1 (0.1 mmol), Cu(CH3CN)4PF6 (0.01 mmol), NaBArF4 (0.012 mmol), (±)-BINAP (0.012 mmol), DCE (2 mL), 40 °C, 12 h, in vials; yields are for the isolated products.
Formed from ynamide substrate 1ag. Ts = p-toluenesulfonyl. MBS = 4-methoxybenzenesulfonyl.