Table 1.
Qualitative and quantitative compositions (%, (w/w)) of emulgel samples.
| Ingredients (INCI Name) |
Function in the Formulation | Content [% m/m] | ||||
|---|---|---|---|---|---|---|
| ASP1 | ASP2 | MAP1 | MAP2 | PE | ||
| Oil phase | ||||||
| Caprylic/capric triglycerides | Emollient | 11.00 | 11.00 | 11.00 | 11.00 | 11.00 |
| Isopropyl myristate | Emollient | 7.50 | 7.50 | 7.50 | 7.50 | 7.50 |
| Olive oil | Emollient | 3.00 | 3.00 | 3.00 | 3.00 | 3.00 |
| Cetearyl alcohol (and) Coco-glucoside |
o/w emulsifier | 7.00 | 7.00 | 7.00 | 7.00 | 7.00 |
| Myristyl alcohol (and) Myristyl glucoside |
o/w emulsifier | 1.50 | 1.50 | 1.50 | 1.50 | 1.50 |
| Active substance | ||||||
| Ascorbyl palmitate | 1.00 | 2.00 | - | - | - | |
| Magnesium ascorbyl phosphate | - | - | 1.00 | 2.00 | - | |
| Water phase | ||||||
| Hydroxyethyl cellulose (HEC) | Thickener/Gelling agent | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Propylene glycol | Humectant | 10.00 | 10.00 | 10.00 | 10.00 | 10.00 |
| Phenoxyethanol (and) Ethylhexylglycerin | Preservative | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Aqua (Water) | Water phase | q.s. 100.00 | q.s. 100.00 | q.s. 100.00 | q.s. 100.00 | q.s. 100.00 |
ASP1, ASP2, MAP1 and MAP 2 indicate emulgels containing 1% and 2% w/w of ascorbyl palmitate and magnesium ascorbyl phosphate, respectively; PE: Placebo emulgel.