Table 4.

Significant associations of the individual rs6573604, rs11621121, rs10483776, and rs4073416 polymorphisms (genetic and allelic model) as well as the rs11621121–rs10483776 haplotypes with the plasma N-glycan levels in the control participants.

Glycan Peak	Model	rs6573604		rs11621121		rs10483776		rs4073416		Haplo-Type
		H/U *	p	H/U *	p	H/U *	p	H/U *	p
GP08 (A2G2)	Genetic	0.06	0.999	9.06	0.215	2.95	0.593	10.26	0.117	H = 26.75; p = 0.101
	Allelic	20754.5	0.978	25454.0	0.059	17330.5	0.333	24352.0	0.020
GP14 (A2G2S1)	Genetic	0.62	0.893	4.61	0.650	5.24	0.475	9.85	0.091	H = 21.39; p = 0.351
	Allelic	19956.5	0.726	26820.0	0.254	16446.5	0.202	24472	0.013
GP22 (FA2G2S2)	Genetic	1.56	0.744	21.00	0.001	22.05	<0.001	14.61	0.039	H = 31.41; p < 0.001
	Allelic	19856.5	0.710	23408.0	0.001	13506.5	<0.001	23952	0.016
GP29 (FA3G3S3)	Genetic	3.99	0.530	4.07	0.464	12.85	0.020	6.99	0.234	H = 28.37; p = 0.020
	Allelic	18026.5	0.167	27664.0	0.333	14608.5	0.003	25248	0.068
GP31 (FA3G3S3)	Genetic	3.94	0.493	8.69	0.169	24.36	<0.001	1.29	0.757	H = 41.19; p < 0.001
	Allelic	18042.5	0.151	25588.0	0.052	13052.5	<0.001	27646	0.397
GP34 (A4G4S3)	Genetic	6.66	0.281	2.57	0.540	13.53	0.013	1.38	0.755	H = 14.39; p = 0.013
	Allelic	17340.5	0.068	27578.0	0.345	14452.5	0.002	28230	0.559
GP36 (A4G4S4)	Genetic	15.13	0.020	4.58	0.563	1.44	0.702	0.41	0.881	H = 23.30; p = 0.256
	Allelic	16010.5	0.003	26752.0	0.341	18606.5	0.781	28718	0.706
GP37 (A4G4S4)	Genetic	15.14	0.013	0.10	0.978	3.50	0.522	0.18	0.912	H = 35.03; p = 0.316
	Allelic	15514.5	0.001	29586.0	0.876	16828.5	0.273	28868	0.743
GP38 (A4G4S4)	Genetic	17.40	0.007	0.85	0.728	1.62	0.666	0.23	0.914	H = 33.42; p = 0.440
	Allelic	15342.5	0.001	28706.0	0.585	17988.5	0.622	29370	0.980

* Data analyzed using the Kruskal–Wallis ANOVA of ranks for the genetic model and represented with the H value, or the Mann–Whitney U test for the allelic model and represented with the U value. Significant p-values (corrected using the Benjamini–Hochberg procedure) are denoted in bold.