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. Author manuscript; available in PMC: 2023 Mar 29.
Published in final edited form as: J Med Chem. 2023 Jan 25;66(3):2116–2142. doi: 10.1021/acs.jmedchem.2c01894

Figure 5.

Figure 5.

Dose–response curves for the effect of 5a (a) and AZM (b) reported as the percentage of recovered IFU. Error bars report standard error of the mean (SEM) (N = 3). (c) Immunofluorescence images for the inhibitory effect of 5a and AZM. Chlamydial inclusions are displayed in green (MOMP - Ctr L2) and HEp-2 cell nuclei in blue (4′,6-diamidino-2-phenylindole (DAPI)). Images were acquired on 20× magnification using an Olympus CKX53 fluorescence microscope with EP50 camera. Channel merge was processed using ImageJ software. UTD: untreated; AZM: azithromycin. Omitted error bars indicate a SD value shorter than the size of the symbol presented in the plots.