Table 3.

Chemical Structures of Dihydrothiazepine Derivatives 9a−d and Their IC50 against C. trachomatis Serovar L2^a,c

compound	R1	R2	R3	IC50 (μg/mL)b
9a	H	H	OCH3	16.08 ± 0.54
9b	H	H	Br	21.35 ± 2.88
9c	H	H	CH3	21.45 ± 0.22
9d	H	H	CN	NI

^aIC₅₀ indicates 50% inhibition of control Chlamydia inclusions. NI: no inhibition seen at the tested concentration range (25−0.39 μg/mL).

^bAll assays were performed in triplicate.

^cIC₅₀ values are also presented in μM and pIC₅₀ units in Table S1. The presented data corresponds to mean ± SD.