Figure 1.

CNV analysis of m6A regulators and identification of prognosis-related m6A-lncRNA. (A) The frequency of CNV mutation analysis revealing the pervasive existence of genetic abnormality in all 23 m6A regulators in PDAC patients. The height of the column represents the mutation frequency. Red dots, amplification frequency; blue dots, deletion frequency. (B) Results of GO annotation analysis revealing the significantly correlated biological processes of 23 m6A regulators. The terms of biological processes are listed along the Y-axis, and the corresponding gene ratios are labeled on the X-axis. The bubble size stands for the number of enriched genes and the color depth stands for the degree of correlation significance. (C) The results of univariate Cox regression analyses were visualized in a forest plot (D). Heatmap presenting the differences in the expression level distributions of prognosis-related m6A-lncRNAs between normal samples (n = 171) and tumor samples (n = 177). * p < 0.05, ** p < 0.01, *** p < 0.001.