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. 2023 Feb 21;11(3):499. doi: 10.3390/vaccines11030499

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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TRAF3IP2-AS1 inhibited PDAC progression in vivo. (A) Procedure of the in vivo experiment. (B) The knockdown efficacy of shRNA was proved by qRT-PCR. (C) Mice were euthanized 21 consecutive days after the subcutaneous injection of transfected tumor cells. (D) Tumors were harvested from the mice after 21 consecutive days. (E) Ki-67 staining showed that the proliferation was more vigorous in tumor specimens from the knockdown group. (F) TUNEL staining showed that the rate of apoptosis was lower within the tumor lesions from the knockdown group. ** p < 0.01.