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. 2023 Feb 21;11(3):199. doi: 10.3390/toxics11030199

Figure 6.

Figure 6

Genotoxicity of non-digested and digested Ag NMs and HEC. Genotoxicity was assessed using the comet assay (a) and 53BP1 assay (b), in HCT116 cells exposed for 24 h to 12.5, 25 or 50 µg/mL of non-digested or digested Ag NMs. Positive controls: 300 µM MMS (comet assay), 18.74 ± 3.62%Tail DNA, 50 µM etoposide (53BP1 assay), fold change 8.13 ± 1.03 relative to control. Statistical significance, exposed vs. control, (**) p <0.01, (***) p < 0.001, (****) p < 0.0001.