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. 2023 Mar 7;9(3):328. doi: 10.3390/jof9030328

Table 3.

Overview of characteristics in naïve and previously eradicated patients.

Categories Total Treatment Status p Value
Naïve Previously Treated
n, (%) n n
Fluoroquinolone (FLQ) resistance 52 (47.3%) 7 45 0.008 *
Clarithromycin (CLA) resistance 57 (52.8%) 7 50 0.002 *
Dual Resistance (FLQ-R and CLA-R) 33 (30%) 4 29 0.054
Mutations
23S mutation 56 (50.9%) 7 49 0.002 *
gyr 91 mutation 21 (19.1%) 3 18 0.268
gyrA mutation 42 (38.2%) 5 37 0.013 *
gyr 87 mutation 16 (14.5%) 3 13 0.757
Histopathological scores
Atrophy score 0.018 *
0 44 18 26
1 57 8 49
2 7 2 5
3 1 0 1
Cellularity score 0.018 *
0 1 1 0
1 39 15 24
2 65 12 53
3 4 0 4
Inflammatory activity 0.002 *
0 8 5 3
1 56 17 39
2 44 6 38
3 1 0 1

*p < 0.05 significance level.