Figure 1.

Schematic representation of PLCζ, briefly (A) summarizes the functional roles of the domains of PLCζ, including the regulatory EF-hands and C2 domains (blue text), and the X and Y catalytic domains (red text) connected by the X-Y linker (green text). (B) PLCζ functional domains, indicates the location of mutations identified in the literature, as indicated by blue arrows. Each mutation is represented by the original amino acid, followed by the amino acid position number, and then the mutated amino acid. Reprinted with permission from Ref. [55]. Copyright 2020 Journal of Assisted Reproduction and Genetics.