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. 2023 Mar 19;13(3):450. doi: 10.3390/metabo13030450

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Correlation between BDNF mRNA expression, serum level of BDNF, and severity of depression symptoms. (a) Correlation between mRNA BDNF expression and BDI, (b) correlation serum level of BDNF and BDI. In IBD subjects in remission, the severity of depression symptoms was correlated positively with BDNF mRNA expression and negatively with BDNF protein concentration (r = 0.363, p = 0.038; r = −0.349, p = 0.046, respectively). Abbreviations: BDI—Beck’s Depression Inventory, BDNF—Brain-Derived Neurotrophic Factor.