Table 3.
Comparison of ECG characteristics and criteria of the test cohort based on Brugada syndrome diagnosis after Sodium Channel Blocker Provocation Test.
| Overall (n = 198) |
Negative SCBPT (n = 150) |
Positive SCBPT (n = 48) |
p Value | |
|---|---|---|---|---|
| Heart rate, bpm | 73.2 ± 14.2 | 73.7 ± 15.1 | 71.6 ± 11.2 | 0.368 |
| p-wave, ms | 104 ± 12.4 | 103.4 ± 12.4 | 106.2 ± 12.4 | 0.178 |
| PR interval, ms | 159.1 ± 23.6 | 157.9 ± 23.5 | 162.8 ± 23.9 | 0.209 |
| QRS duration, ms | 97.4 ± 7.4 | 97.2 ± 6.2 | 98.2 ± 10.4 | 0.410 |
| QT interval, ms | 386.5 ± 25.2 | 385.6 ± 25.9 | 389.5 ± 23.2 | 0.358 |
| QTc interval, ms | 418.8 ± 31.2 | 417.6 ± 33.2 | 422 ± 23.9 | 0.328 |
| P axis, ° | 56.3 ± 21.4 | 57.2 ± 21.7 | 53.4 ± 20.4 | 0.291 |
| QRS axis, ° | 41.4 ± 32.6 | 43.3 ± 34.3 | 36 ± 26.8 | 0.184 |
| T axis, ° | 46.6 ± 21.5 | 45.80 ± 28.9 | 49.06 ± 23.2 | 0.360 |
| Measurability of r’-wave at: | ||||
| IV° ic, % (n) | 7.6 (15) | 4 (6) | 18.8 (9) | 0.001 |
| III° ic, % (n) | 20.2 (40) | 16.7 (25) | 31.3 (15) | 0.029 |
| II° ic, % (n) | 33.3 (66) | 22.7 (34) | 66.7 (32) | <0.0001 |
| Major β- angle | 43.3 ± 16.7 | 34.3 ± 14.9 | 53.1 ± 12.6 | <0.0001 |
| Major α- angle | 32.9 ± 14.9 | 25.3 ± 12.5 | 41.4 ± 12.7 | <0.0001 |
| Major DBT- 5 mm | 196.1 ± 126.2 | 149 ± 144.1 | 247.5 ± 76.9 | <0.0001 |
| Major DBT- iso | 90.5 ± 34.5 | 74.6 ± 24.4 | 107.9 ± 35.8 | <0.0001 |
| Major triangle base/height | 1.3 ± 0.7 | 1.1 ± 0.6 | 1.4 ± 0.7 | 0.03 |