Table 3.
Cytokine, chemokine, and growth factor levels in SFs from OA (n = 7), RA (n = 6), PsA (n = 12), and CIA patients (n = 10).
| OA | RA | PsA | CIA | p | |
|---|---|---|---|---|---|
| IL-1β, pg/mL (IQR) | 0.4 (0.1–0.6) | 10 (1.9–29) * | 1.2 (0.8–2.3) ° | 13 (4.0–24) * | 0.0001 |
| IL-6, pg/mL (IQR) | 90 (73–171) | 4119 (182–13,852) | 1070 (164–5043) | 22,512 (2986–48,255) # | 0.007 |
| IL-8, pg/mL (IQR) | 20 (6.9–41) | 2872 (204–6095) # | 222 (185–380) | 934 (256–1815) # | 0.001 |
| IL-10, pg/mL (IQR) | 1.0 (0.9–3.1) | 30 (14–45) * | 5.0 (3.3–10) § | 15 (7.8–25) * | 0.0001 |
| TNF, pg/mL (IQR) | 0.0 | 2.7 (0.3–9.8) # | 0.0 (0.0–0.2) § | 0.0 (0.0–4.2) | 0.009 |
| TGFβ, pg/mL (IQR) | 1357 (875–2031) | 2633 (1152–3317) | 708 (412–1587) | 1256 (652–3536) | ns |
Data are expressed as the median and interquartile range (IQR) and p is calculated according to the Kruskal–Wallis test. Dunn’s post hoc test: # p < 0.01, * p < 0.001 vs. OA, ° p < 0.05 vs. CIA, § p < 0.05 vs. RA. Abbreviations are as follows: OA, osteoarthritis; RA, rheumatoid arthritis; PsA, psoriatic arthritis; CIA, crystal-induced arthritis; ns, not significant.