Table 5.
Features | Peptide #2 | Peptide #3 | Peptide #5 | Peptide #7 |
---|---|---|---|---|
Sequence | EETFHGVL | NVVELNVAPGDK | IVASVGSA | GEFALCSAKT |
CPP (cell-penetrating peptides) 1 | No | No | No | No |
Antibacterial activity (probability) 2 | 30.5% | 5.7% | 35% | 43.1% |
Antifungal activity (probability) 2 | 5.9% | 4.4% | 19% | 48.8% |
Antibiofilm activity 3 | Yes | No | No | No |
Hemolytic potential (probability) 4 | 0.49 | 0.49 | 0.49 | 0.48 |
Toxicity 5 | No | No | No | No |
Degradation by tripsin 6 | No | Yes | No | Yes |
Degradation by pepsin (pH = 1.3) 6 | Yes | Yes | No | Yes |
Degradation by pepsin (pH > 2) 6 | Yes | Yes | No | Yes |
1 CPP (cell-penetrating peptides): https://webs.iiitd.edu.in/raghava/cellppd/index.html, URL (accessed on 1 April 2022). 2 iAMPpred: http://cabgrid.res.in:8080/amppred/index.html, URL (accessed on 1 April 2022) 3 dPABBs: https://ab-openlab.csir.res.in/abp/antibiofilm/index.php, URL (accessed on 1 April 2022) 4 HemoPI: https://webs.iiitd.edu.in/raghava/hemopi/index.php, URL (accessed on 1 April 2022) 5 ToxinPred: https://webs.iiitd.edu.in/raghava/toxinpred/index.html, URL (accessed on 1 April 2022) 6 Peptide cutter server: https://web.expasy.org/peptide_cutter, URL (accessed on 1 April 2022).