Table 2.

Association between rs599839 polymorphism and cardiovascular diseases.

Model	Random Effect	Z p-Value	Q Test p-Value	I2	Egger Test p-Value
Overall
G	Reference
A	1.27 (1.11–1.44)	1 × 10−4	1 × 10−4	80.82	0.100
A *	1.19 (1.13–1.26)	1 × 10−4	0.175	30.38	0.108
GG c	Reference
GA c	1.11 (0.92–1.35)	0.28	0.155	31.70	0.100
AA c	1.33 (1.00–1.75)	0.045	0.009	58.90	0.100
GG d	Reference
GA+AA d	1.25 (0.98–1.59)	0.064	0.019	53.15	0.300
GA+AA d*	1.22 (1.06–1.39)	3 × 10−3	0.141	34.63	0.446
GG+GA r	Reference
AA r	1.29 (1.12–1.49)	1 × 10−4	1 × 10−4	76.65	0.103
AA r*	1.23 (1.15–1.32)	1 × 10−4	0.423	1.30	0.175
CAD
G	Reference
A	1.30 (1.11–1.51)	1 × 10−4	1 × 10−4	81.22	0.100
A *	1.17 (1.10–1.24)	1 × 10−4	0.265	21.54	0.310
GG c	Reference
GA c	1.18 (1.00–1.39)	0.039	0.340	11.7	0.100
AA c	1.51 (1.14–2.00)	4 × 10−3	0.041	54.2	0.100
AA c*	1.39 (1.18–1.65)	1 × 10−4	0.325	13.66	0.614
GG d	Reference
GA+AA d	1.39 (1.08–1.79)	0.010	0.037	52.97	0.104
GA+AA d*	1.24 (1.08–1.42)	2 × 10−3	0.153	36.11	0.301
GG+GA r	Reference
AA r	1.32 (1.12–1.56)	1 × 10−3	1 × 10−4	75.99	0.100
AA r*	1.20 (1.11–1.29)	1 × 10−4	0.645	0.000	0.386
Asian population
G	Reference
A	1.32 (1.12–1.57)	1 × 10−3	1 × 10−4	80.70	0.290
A *	1.27 (1.18–1.36)	1 × 10−4	0.494	0.000	0.236
GG c	Reference
GA c	0.84 (0.60–1.16)	0.288	0.600	0.000	0.340
AA c	1.29 (1.29–1.30)	0.260	0.060	43.48	0.320
AA c*	1.07 (0.77–1.49)	0.676	0.424	1.201	0.653
GG d	Reference
GA+AA d	1.12 (0.81–1.55)	0.466	0.112	37.12	0.323
GG+GA r	Reference
AA r	1.34 (1.14–1.59)	1 × 10−4	1 × 10−4	77.79	0.324
AA r*	1.30 (1.21–1.40)	1 × 10−4	0.629	0.000	0.333

^c: codominant; ^d: dominant; ^r: recessive. * Model without heterogeneity.