Table 3.

Main effects of the model of BBB disruption, treatment and sex and their interaction effects on CSF glutamate level. No significance (n-s).

Effect	Glutamate 0.423 g/kg vs. Placebo	Glutamate 0.845 g/kg vs. Placebo	Glutamate 1.69 g/kg vs. Placebo	TBI 6 h vs. Control	TBI 24 h vs. Control	HOBBB vs. Control
Models of BBB disruption	p < 0.01	p < 0.01	p < 0.01	p < 0.01	p < 0.01	p < 0.01
Treatment	p < 0.01	p < 0.01	p < 0.01	p < 0.01	p < 0.01	p < 0.01
Sex	n-s	n-s	n-s	n-s	n-s	n-s
Models of BBB disruption × treatment	p < 0.01	p < 0.01	p < 0.01	p < 0.01	p < 0.01	p < 0.01
Models of BBB disruption × sex	n-s	n-s	n-s	n-s	n-s	n-s
Models of BBB disruption × sex × treatment	n-s	n-s	n-s	n-s	n-s	n-s
Treatment × sex	n-s	n-s	n-s	n-s	n-s	n-s