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Group setting and corresponding antibiotic addition plan.
| Code | Name | Treatment | Concentration (µg/mL) | |
|---|---|---|---|---|
| CIP | PMB | |||
| a | Control | no antibiotic | – | – |
| b | PMB–SD | add PMB–SD at time zero | – | 1 |
| c | CIP–SD | add CIP–SD at time zero | 32 | – |
| d | PMB–CIP–SD | add PMB–SD and CIP–SD at time zero | 32 | 1 |
| e | PMB–SD–CIP–SD | add PMB–SD at the beginning then add CIP–SD added after 24 h | 32 | 1 |
Concentrations of CIP and PMB tested corresponded to pure drug formulations.
