Table 6.
Adjusted and unadjusted relationships between treatment failure, dropout at SVR assessment stage, and socio-economic, demographic, clinical, behavioral, and hospital characteristics factors.
| Treatment Failure | Dropout at SVR Assessment Stage | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | Unadjusted model | Adjusted model † | Unadjusted model | Adjusted model † | ||||||
| OR | 95% CI | OR | 95% CI | N | OR | 95% CI | OR | 95% CI | ||
| Baseline viral load | 9332 | 1.12 | 1.04, 1.39 | 1.14 | 1.02, 1.28 | - | - | - | - | - |
| Age | ||||||||||
| <44 | 1227 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 | 1591 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 |
| 44–54 | 1262 | 1.02 | 0.79, 1.32 | 1.34 | 0.93, 1.91 | 1571 | 1.02 | 0.83, 1.26 | 1.1 | 0.88, 1.39 |
| 55–64 | 2343 | 0.94 | 0.75, 1.18 | 1.18 | 0.86, 1.63 | 2968 | 0.96 | 0.80, 1.15 | 1.11 | 0.91, 1.35 |
| 64+ | 4500 | 0.94 | 0.76, 1.15 | 1.12 | 0.82, 1.53 | 6754 | 1.9 | 1.63, 2.23 | 1.42 | 1.17, 1.72 |
| Sex | ||||||||||
| Female | 5654 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 | 7939 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 |
| Male | 3678 | 1.01 | 0.87, 1.16 | 1.1 | 0.90, 1.33 | 4945 | 0.81 | 0.73, 0.90 | 0.76 | 0.67, 0.85 |
| SES | ||||||||||
| Category 1 | 1835 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 | 2573 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 |
| Category 2 | 2541 | 0.97 | 0.79, 1.18 | 0.98 | 0.76, 1.25 | 3296 | 0.89 | 0.77, 1.03 | 0.96 | 0.82, 1.14 |
| Category 3 or 4 or unknown | 3224 | 1.15 | 0.95, 1.40 | 1.13 | 0.88, 1.45 | 5174 | 0.64 | 0.56, 0.73 | 0.73 | 0.62, 0.84 |
| Missing | 1732 | 1.41 | 1.12, 1.78 | 0.61 | 0.43, 0.86 | 1841 | 3.58 | 3.01, 4.26 | 2.53 | 2.08, 3.08 |
| HIV positive | ||||||||||
| No | 7795 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 | 11,075 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 |
| Yes | 922 | 0.8 | 0.62, 1.03 | 1.09 | 0.81, 1.46 | 1125 | 0.31 | 0.25, 0.38 | 0.3 | 0.24, 0.38 |
| Missing | 615 | 5.92 | 4.73, 7.40 | 0.77 | 0.20, 3.01 | 684 | 0.076 | 0.05, 0.13 | 0.059 | 0.03, 0.11 |
| HBV Ag positive | ||||||||||
| No | 8873 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 | 12,291 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 |
| Yes | 140 | 1.27 | 0.79, 2.05 | 1.11 | 0.57, 2.18 | 274 | 0.86 | 0.57, 1.31 | 0.6 | 0.37, 0.99 |
| Missing | 319 | 2.8 | 2.00, 3.92 | 1.48 | 0.84, 2.63 | 319 | 0.73 | 0.54, 0.99 | 0.79 | 0.50, 1.22 |
| Cirrhotic | ||||||||||
| No | 8898 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 | 12,440 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 |
| Yes | 434 | 1.12 | 0.81, 1.54 | 1.71 | 1.20, 2.43 | 444 | 0.066 | 0.03, 0.13 | 0.059 | 0.03, 0.12 |
| Family history of viral hepatitis C | ||||||||||
| No | 8220 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 | 11,376 | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 |
| Yes | 437 | 1.57 | 1.17, 2.12 | 1.57 | 1.10, 2.25 | 721 | 0.42 | 0.30, 0.57 | 0.14 | 0.08, 0.24 |
| Missing | 675 | 5.96 | 4.79, 7.42 | 3.62 | 1.07, 12.31 | 787 | 0.66 | 0.53, 0.81 | 0.18 | 0.08, 0.39 |
| Ever been medically operated on | ||||||||||
| No | 8351 | 1 | 1.00, 1.00 | - | - | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 | |
| Yes | 306 | 1.34 | 0.90, 1.97 | - | - | 0.57 | 0.47, 0.68 | 0.39 | 0.27, 0.56 | |
| Missing | 675 | 5.8 | 4.71, 7.29 | - | - | 1.21 | 0.56, 1.40 | 1.44 | 0.89, 2.32 | |
| HBV vaccination status | ||||||||||
| Not vaccinated | 6985 | - | - | - | 1 | 1.00, 1.00 | 1 | 1.00, 1.00 | ||
| Partially or fully vaccinated | 2347 | - | - | - | - | 0.11 | 0.09, 0.13 | 0.14 | 0.11, 0.16 | |
† Controlled for marital status, health insurance, hypertension, diabetes, and total number of staff.