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Pharmacokinetic (ADMET) properties of cubebol and bornyl acetate compounds.
| Absorption | Distribution and Metabolism CYP450 |
Excretion and Toxicity | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Skin Permeability | Intestinal Absorption | CaCO2 Permeability |
3A4 Substrate |
3A4 Inhibitor | 6D6 Substrate | 6D6 Inhibitor | VDss | BBB | Total Clearance | AMES | Hepatotoxicity | |
| Cubebol | −2.17 | 94.94 | 1.32 | yes | no | no | no | 0.45 | 0.66 | 0.88 | no | no |
| Bornyl acetate | −2.23 | 95.36 | 1.85 | no | no | no | no | 0.30 | 0.55 | 1.03 | no | no |
