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. 2023 Mar 18;24(6):5815. doi: 10.3390/ijms24065815

Figure 1.

Figure 1

Changes in refraction, axial length (AL), and choroidal thickness (CT) in lens-induced myopia (LIM) mice administered native-lactoferrin (nLF) and its derivatives. (a) Changes in refraction in 0 D and −30 D eyes over a 3-week period. (b) Changes in AL in 0 D and −30 D eyes over a 3-week period. (c) Changes in choroidal thickness in 0 D and −30 D eyes over a 3-week period. (d) Delta between the refractive changes in 0 D and −30 D eyes over a 3-week period. (e) Delta between the AL changes in 0 D and −30 D eyes over a 3-week period. (f) Delta between the choroidal thickness changes in 0 D and −30 D eyes over a 3-week period. n = 10 per group. * p < 0.05, ** p < 0.01, and **** p < 0.0001. The two-tailed Student’s t-test was used for left-right comparison analysis. Comparisons between PBS, LF, pepsin + LF, and trypsin + LF groups in each experiment was analyzed by analysis of variance and Tukey’s post hoc test. The values are represented as mean ± SE.