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. 2023 Mar 18;24(6):5815. doi: 10.3390/ijms24065815

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Changes in refraction, axial length (AL), and choroidal thickness (CT) in lens-induced myopia (LIM) mice administered native-lactoferrin (nLF) and Holo-LF. (a) Changes in refraction in 0 D and −30 D eyes over a 3-week period. (b) Changes in axial length (AL) in 0 D and −30 D eyes over a 3-week period. (c) Changes in choroidal thickness in 0 D and −30 D eyes over a 3-week period. (d) Delta between the refractive changes in 0 D and −30 D eyes over a 3-week period. (e) Delta between the AL changes in 0 D and −30 D eyes over a 3-week period. (f) Delta between the choroidal thickness changes in 0 D and −30 D eyes over a 3-week period. n = 10 per group. * p < 0.05, and **** p < 0.0001. The two-tailed Student’s t-test was used for left–right comparison analysis. Group comparisons were analyzed by analysis of variance and Tukey’s post hoc test. The values are represented as mean ± SE.