Figure 6.

(a) Chemical structures of the molecular structure of PyTPE-CRP and the process of diagnosing and eliminating macrophage-mediated intracellular bacterial infections. (b) Confocal images showing the localization of PyTPE-CRP 60 min after Raw 264.7 macrophages were infected with S. aureus (MOI = 20). (c) Confocal images of ROS detection inside the macrophages using DCF-DA after bacterial infection in the presence of PyTPE-CRP. (d) Intracellular survival of S. aureus inside Raw 264.7 macrophages in the presence of PyTPE-CRP at different concentrations without and with light irradiation for 10 min at 40 mW cm⁻². (e) MIC of PyTPE-CRP towards extracellular S. aureus without and with light irradiation (40 mW cm⁻², 10 min). Adapted from [90], copyright 2019, Wiley-VCH.